The organ of Zuckerkandl refers to a small group of chromaffin cells located at the base of the aorta in the abdomen. These cells are part of the sympathetic nervous system and secrete adrenaline and noradrenaline directly into the bloodstream. The organ of Zuckerkandl is named after the Austrian pathologist, Emil Zuckerkandl, who discovered it in 1901. While its function is not fully understood, it is believed to play a role in regulating blood pressure and heart rate during times of stress or physical activity. The organ of Zuckerkandl can also be the site of tumors, which may cause excessive secretion of catecholamines resulting in various symptoms such as high blood pressure, palpitations, and headaches.
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